Structure & Function

Human skin anatomy, transparent cross-section with skin receptors, 3D ...

The integumentary system is the body’s outer protective covering and includes all structures that make up the skin and its related components.

It is composed of:

  1. Skin — the main organ, consisting of:

    • Epidermis: the outermost layer made mostly of keratinized stratified squamous epithelium.

    • Dermis: the thicker inner layer containing connective tissue, blood vessels, nerves, glands, and hair follicles.

    • (Sometimes the hypodermis or subcutaneous layer is included; it lies beneath the skin and contains fat and connective tissue.)

  2. Accessory structures (skin appendages):
    • Hair — provides protection and helps with temperature regulation.

    • Nails — protect the fingertips and aid in grasping.

    • Sweat glands (sudoriferous glands) — help regulate body temperature by secreting sweat.

    • Sebaceous glands — produce sebum (oil) that lubricates and waterproofs the skin and hair.

  3. Associated sensory receptors — detect touch, pressure, pain, and temperature.

 

The physiology of the integumentary system centers on maintaining barrier integrity, thermoregulation, sensation, immunity, metabolism, and repair.

 

 

Integumentary System

Digital World Medical School
© 2025